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De Gruyter

NADP is used in many anabolic metabolic reactions (constructing macromolecules from smaller units), including fatty acid synthesis and chain elongation, cholesterol synthesis and nucleic acid synthesis

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This essential amino acid is a precursor to L-carnitine, another amino acid with fat-burning activities that takes place in the liver

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Moreover, wild-type TP53 appears to negatively control the mTOR pathway and the PPP, therefore governing fatty acid synthesis (175, 176)