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10 In particular, semaglutide was most successful at reducing alanine transaminase (mean difference, 14.70 U/L), aspartate transaminase (mean difference, 9.32 U/L), g-glutamyl transferase (mean difference, 16.56 U/L), and liver stif fness measurement (mean difference, 3.08 kPa) compared with the other medications studied, whereas liraglutide demonstrated efficacy in reducing subcutaneous adipose tissue (mean difference, 30.27 cm 2 ) and liver fat fraction (mean difference, 5.16%)

Everythingconsultation, prescription, support, and medication deliveryis done online, allowing users across the country to begin GLP-1 treatment without disruption

Preliminary investigations of GLP-1 agents in patients with both conditions have reported modest improvements in inflammatory markers, though these studies are small and not designed to establish efficacy for RA

The pharmaceutical company Novo Nordisk, semaglutides manufacturer, funded this study