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According to American College of Gastroenterology guidelines, the presence of alarm features or persistent symptoms despite appropriate therapy warrants endoscopic evaluation

Voy outcome data: JMIR, 2025 (N=125,000+)

These predispositions may help provide context for your provider's discussion about candidacy, dosing, and side effect patterns, but clinical evaluation remains essential

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therefore, TriNetX federated network has been granted a waiver from the Western institutional review board, including the Thomas Jefferson institutional review board