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tirzepatide remain to be reported, an open-label 40-week study in type 2 diabetes patients (SURPASS-2) and recent meta-analyses have suggested greater weight loss (up to 22%) achieved with tirzepatide as compared to semaglutide (15-18%)

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Whether this observation is solely the consequence of translocation of Parasutterella bacteria from the intestine to the EWAT or driven by more indirect mechanisms such as bacterially-produced metabolites 85 is yet to be determined

BPC-157s human trials were early-phase IBD