(2022) 17:e0262714
PMID: 41471311
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Acknowledgements This work was supported by the National Key R&D Program of China (2023YFC2705802 to J.W.), the National Natural Science Foundation of China (82573812 to C.C.), the Natural Science Foundation of Hubei Province (2025AFB580 to C.C.), the Foundation of Tongji Hospital, China (2023CXZH014 and 25-2KYC13057-18 to C.C.), and the China Postdoctoral Science Foundation (2025M782382 to M.X.)
It also regulates and supports detoxification and toxin elimination, energy levels, and healthy aging
How PTD-DBM Works for Hair Directly activates the Wnt/-catenin pathway, which is suppressed by DHT in androgenetic alopecia Inhibits CXXC5 a negative regulator of the Wnt pathway effectively unblocking the hair growth signal Promotes the conversion of vellus hairs (thin, fine hairs) back into terminal hairs (thick, pigmented hairs) Does not directly interfere with systemic hormones, reducing the risk of sexual side effects associated with finasteride What the Research Says Research from Yonsei University in South Korea demonstrated that PTD-DBM promoted new hair growth in mice within 28 days of topical application