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Any claim that one outperforms the other is cross-trial inference, not a measured result
Available online at: 39 MakKMShekharAC
KPV has limited long-term data Most KPV evidence comes from laboratory and animal research rather than long-term human studies
Nrf2 also regulates the expression of genes that control inflammatory and immune system responses (Kasprzak et al., 2020)
Endothelial injury generated directly by intracellular viral replication and by ACE2 downregulation, exposing cells to angiotensin II in the absence of the modulator effects of angiotensin 17 (Vinciguerra et al., 2020), and vascular chronic inflammation promoting the development of tissue macrophages overloaded by cholesterol (foam cells), both increase the possibility of acquiring a severe COVID-19 infection (Vinciguerra et al., 2020
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