Garon E, Johnson M, Lisberg A, Spira A, Yamamoto N, Heist R, et al
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Oestrogen dependence may be due to the upregulation of the 17-hydroxysteroid dehydrogenase-1 and aromatase genes, whereas progesterone resistance may result from the failure of progesterone receptor activation and transcription of progesterone target genes [99]
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We used fasting samples from well-characterized populations from two large phase 3 randomized controlled trials