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Stopping retatrutide will not immediately stop shedding (the telogen transition already happened) and may lead to weight regain that creates additional metabolic stress

consequently, people are taking the drug off-label

This guide walks you through the most frequently reported side effects, explains what is considered normal during titration, and outlines the warning signs that should prompt a call to your provider

Fatigue reported by 15-20% of people

Total daily dose: Weeks 14 at 500 mcg total , then Weeks 58 at 1000 mcg total , once daily (or 5 days on, 2 off)

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