Data were collected from a 20-week pilot trial (NCT05786521), which randomized 20 older adults (72.7 4.8 years of age, 50% women, 45% Hispanic) living with prediabetes/diabetes (hemoglobin A1C 5.7%7.5%) and overweight/obesity [body mass index (BMI): 32.9 4.0 kg/m 2 ] to 1.0 mg/weekly semaglutide + lifestyle counseling (n = 10) or lifestyle counseling alone (n = 10)
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It is a structured clinical sequence built on published evidence, adapted to the specific skin biology of our patient population, and refined through practice
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Its also essential to note that gelatin alone cannot repair damaged cartilage or reverse advanced osteoarthritis
These differences support the need for gender-specific nutritional guidelines, especially in combination with pharmacological therapies