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In the SURMOUNT-4 trial, participants who discontinued tirzepatide regained much of the weight they had initially lost (Cornell Chronicle)

Most patients (97%) were treated with one or more glucose lowering medications at baseline: metformin (76%), insulin (51%), SGLT-2 inhibitor (27%), sulfonylurea (29%), and DPP-4 inhibitor (23%)

These soften stool without forcing unnatural contractions

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Visible results often appear gradually over several weeks or months depending on the frequency of treatments and the individual metabolism of the patient

Potency, purity, and consistency can vary between compounding pharmacies and even between batches