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Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression
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12 Preclinical data also have shown that it rapidly increases mGlu2 receptor expression via histone acetylation, leading to sustained antidepressant-like effects
doi: 10.1073/pnas.1007816107 114 ChengSCQuintinJCramerRAShepardsonKMSaeedSKumarVet al
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