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One study in healthy rat brain mitochondria also did not observe any direct effect of trimetazidine on mitochondrial permeability transition [143]
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4.1 Risks of supplement use during chemotherapy The use of natural remedies during chemotherapy in breast cancer is a compound scenario that includes the safety issue as well as drugsupplement interferences and merits meticulous assessment, because these interventionsusually considered as harmless substancesmay significantly alter the pharmacokinetic/pharmacodynamic response, antitumoural activity, and toxicity profile to conventional oncologic treatment (200)
In vivo and in vitro anti-diabetic activity of ethanolic propolis extract
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