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Role of Transcription Factor NRF2 in Oxidative Stress Responses A major response to the accumulation of reactive oxidants, such as ROS and RNS, is the activation of a transcription factor identified as NRF2 [nuclear factor erythroid 2 (NFE2)related factor 2]

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It was also supported by National Key Research and Development Plan by the Ministry of Science and Technology in China (2017YFC1308602)

Both structural and functional analyses revealed Cagris non-selective activation of G s signaling pathways through CTR and AMY 1 R