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At present, several studies have found that GLP-1 analog Lira may improve lipid metabolism and fat deposition by downregulating the expression of lipid metabolism-related genes FAS, and ACC-a mRNA, or promoting the expression of PI3K protein in mouse liver

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Published results have reported mean body weight reductions of approximately 20-22% from baseline at the highest studied doses exceeding published results for semaglutide at comparable timepoints