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Only the concentration values change

L-theanine helps promote alpha brain waves, which are associated with relaxed alertness

Previous AngIV analogs, while showing promise in animal models of dementia, were hindered by poor metabolic stability indicated by a short half-life, and an inability to cross the BBB due to their peptide nature

Consistent with this, increased expression levels of SLC7A5 have been observed in various types of cancer such as breast cancer [45], KRAS-mutated CRC [46], gastric cancer [47], lung cancer [48], pancreatic cancer [49], prostate cancer [50], melanoma [51], ovarian cancer [52] and hepatocellular carcinomas [53], and esophageal cancer [54]

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The most successful approach to date focuses on apoptosis, where the combination of the BCL-2 inhibitor venetoclax and hypomethylating agents has improved outcomes for elderly patients with AML or those ineligible for intensive chemotherapy