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Chronic Insomnia: In an open-label study involving patients with severe chronic insomnia, a treatment regimen of 10 intravenous injections of DSIP (25 nmol/kg) resulted in a normalization of sleep patterns that persisted for follow-up periods of 3 to 7 months.Crucially, the patients reported not just improved sleep duration, but improved daytime mood and performance, distinguishing DSIP from benzodiazepines which often cause daytime drowsiness and cognitive impairment
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Following clearance by centrifugation, protein concentration of lysates was determined using a Pierce BCA protein assay (23225, Fisher Scientific) and 30 g of lysate was prepared using 4 LDS sample buffer (Thermo Fisher) and 10% 2-mercaptoethanol and run on NuPAGE 415% BisTris gels (Thermo Fisher)
& Mucida, D
It is classified as an unapproved new drug , meaning it cannot be legally marketed, sold, or prescribed as a therapeutic agent
