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References This article is based on research from peer-reviewed medical journals, FDA documentation, manufacturer prescribing information, and clinical guidelines

Some individuals may not feel any immediate difference, while others notice a gradual decrease in appetite or an earlier feeling of fullness during meals

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Animal studies All rodent studies were approved either by the Gteborg Preclinical Ethical Committee for AstraZeneca (Sweden), the Institutional Animal Care and Use Committee at MedImmune (Gaithersburg, MD, USA) in accordance with US Animal Welfare Act guidelines, Home Office licences for studies performed at MedImmune (Cambridge, UK), or under personal licenses issued by the Danish Committee for Animal Research for studies performed at Gubra (Horsholm, Denmark)

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