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Franca L, Suescun M, Miranda J, Giovambattista A, Perell M, Spinedi E, et al

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confirmed the enhanced percentage of eryptosis in HD patients and reported a positive correlation between the percentage of circulating eryptotic cells and ROS and ceramide concentrations, and between the percentage of PS-exposing erythrocytes and both erythropoietin dosage and the percentage of reticulocytes [265]

Figure 6: Photograph of Sir Frederick Banting and Charles Best with dog 408 taken in August 1921 by Henry Mahon on the roof of the University of Torontos Medical Building