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Researchers gave 32 men with ED a combination of intranasal PT-141 (either 7.5 or 10 mg) plus oral sildenafil (50 or 100 mg), then used a RigiScan device to objectively measure erectile rigidity over 6 hours.Impressively, adding PT-141 to sildenafil increased the duration of erectile activity by over five-fold compared to sildenafil alone

In animal studies, TB500 has shown the ability to stimulate the regeneration of damaged cardiac muscle, a phenomenon critical in the recovery from heart-related issues

In models where nerves have been transected or crushed, treatment with the peptide has led to accelerated functional recovery, improved nerve conduction, and enhanced histological signs of healing

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