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Ethics statement The animal study was approved by Oujiang Laboratory Animal Ethics Committee

Kashyap MP, Roberts C, Waseem M, Tyagi P (2018) Drug Targets in Neurotrophin Signaling in the Central and Peripheral Nervous System

York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, OMalley BW

Although NR has shown promising results in this context, further studies are necessary to establish the efficacy and safety of NR in HF patients

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