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In this model, successful repair proceeds through natural reprogramming of epithelial cells to a more embryonic-like state, marked by the murine stem cell marker Ly6a (encoding SCA1) 22,59,60

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Therapeutic effects in hypoxic osteosarcoma cells The biological activities of NP4 were studied against human osteosarcoma (143B) and mouse osteosarcoma (K7M2) cells with different O 2 concentrations

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