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Group A exhibited the higher BES score [Group A: 24.0 (22.025.5)

Indirect comparison across trials suggests tirzepatide produces greater weight loss at currently approved doses

This pattern is so common that researchers have given it a name: the GI tolerance paradox

Treatment typically begins at 2.5 mg weekly (an initiation dose not intended for glycemic control), with gradual dose escalation every four weeks to minimize gastrointestinal side effects

The impact of sleep and circadian disturbance on hormones and metabolism

We conclude that semaglutide improves glycemic control with automated insulin delivery compared to placebo