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Immediate Storage Put the medication vial back into the refrigerator immediately after use

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Two key contributors: blood sugar reduction (even modest drops can cause tiredness during adaptation) and dehydration, since electrolyte imbalance prevents water from reaching cells even when fluid intake seems adequate

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Less Common of Semaglutide Side Effects There have been reports of peripheral neuropathy (nerve damage in the extremities) associated with semaglutide use