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Melanotan II is non-selective across melanocortin receptors, which is why it is reported to also affect appetite and sexual arousal via MC3R/MC4R, and it is not approved anywhere

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Diabet Med 2012;29:12601267

19 Histopathology The lesions mimic a tumor of follicular infundibulum or superficial BCC by virtue of anastomosing cells that connect broadly to the basal layer of epidermis and have an orientation parallel to the epidermal surface

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Some comes from the GLP-1 hormonal effects