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Similarly, bile acid treatment rescued microbial diversity and restored 5-HT, DA, acetylcholine, BDNF, and tropomyosin receptor kinase B levels in both brain and gut of zebrafish, alleviating behavioral symptoms (Qian et al., 2025)
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Notably, semaglutide is not recommended for patients with severe gastrointestinal disease, such as severe gastroparesis, per FDA labeling
It affects the control of blood sugar
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