En los tratamientos con Ozempic y su equivalente local, la dosis inicial se ajusta progresivamente hasta alcanzar el mximo de 1 mg por semana
Appetite changes come first, followed by weight loss that tends to build as the dose increases over several months
Note: animal studies indicate that high doses of DPP-4 inhibitors & GLP-1 agonists cause expansion of cells of the pancreatic ductal glands and can cause premalignant pancreatic intraepithelial lesions (PanIN) that have the potential to progress to pancreatic adenocarcinoma
Patients should be counselled to recognise symptoms of these serious complications and seek immediate medical attention if they occur
Stay Informed: As these GLP-1 drugs get more popular, medical aestheticians need up-to-date skills
TRT may also slightly improve baseline metabolic rate, which can enhance the weight loss response to GLP-1 agents by 510% in some studies, though individual variation is substantial