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Often linked to mitochondria and oxidative stress
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Vitamin C gp phn bo v chc nng no b c tnh chng oxy ha ca vitamin C c th mang li li ch cho chc nng no b bng cch c ch qu trnh stress oxy ha v cc phn ng vim gn no, ct sng v dy thn kinh (c gichung l h thn kinh trung ng)
This validated the in vitro model as representative of age-related Leydig cell dysfunction
However, when oxidative stress becomes prolonged and cellular systems are no more able to counteract the oxidative-mediated insults, the amount of free GSH decreases leading to irreversible cell degeneration and death
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