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Nearly 4% of users who reported side effects mentioned menstrual changes, things like irregular cycles, heavy bleeding, or intermenstrual bleeding, and these symptoms arent prominently featured in the current prescribing information. When you consider that were looking at a mixed-gender sample on Reddit, and that Reddit skews male, the true rate among women taking these medications could potentially be higher, Sehgal said

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Kubelis-Lpez DE, Zapata-Salazar NA, Said-Fernndez SL et al (2021) Updates and new medical treatments for vitiligo (Review)