Among the carrier types, liposomes can reduce immune clearance and prolong circulation time through PEGylation modification (Aparicio-Lopez et al., 2024), while liposomes modified with targeting ligands (such as folic acid or EGFR antibodies) can further achieve active targeting (Petrikaite et al., 2023)
However, the cancer has spread to distant lymph nodes or organs such as the lungs, liver, or brain
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Additionally, to our knowledge, this is the first network meta-analysis concerning the association between GLP-1 RAs and gastrointestinal adverse events in the population with overweight or obesity, as these evaluations have been predominantly conducted in diabetic patients
These symptoms require urgent medical attention
There is a theoretical concern that prolonged use of semaglutide could lead to an increased risk of gallbladder disorders, including gallstones (cholelithiasis), inflammation (cholecystitis), and biliary sludge