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Across phenotypes, our data indicate an association between rs1800437 and tirzepatide treatment for both the vomiting and nausea phenotypes, and potentially constipation, but the variant does not seem to influence efficacy ( P = 0.73

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Fluoxetine, on the other hand, is an SSRI (Selective Serotonin Reuptake Inhibitor) that is mainly used to treat depression, anxiety, and other mental health disorders

Internet: (accessed Jan 28, 2026)

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doi: 10.1038/s41597-023-02100-7