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These medicines are available as injections given daily or weekly, and some (such as Rybelsus) are available as pills
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As a consequence, levels of adherence are lower than for people with diabetes, as demonstrated by another study that applied the same metric of adherence to people using GLP-1s to treat obesity: 40.1% for Ozempic (semaglutide, Novo Nordisk), 31.5% for weekly injectable Wegovy and just 15% for daily injectable Saxenda (liraglutide, Novo Nordisk).10 This suggests that greater expectation management is required to maintain users faith in the value and purpose of what they are doing
Histopathological and experimental findings suggest that structural gonadal alterations and epigenetic changes may contribute to prolonged fertility impairment
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