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Long-Term Maintenance Plan Weight regain after stopping GLP-1 medications is a well-documented challenge

As the program continues, the changes become more noticeable, with significant weight loss typically occurring over several months

For high-fat diet experiments, mice were fed a 60 kcal% fat high-fat diet (Research Diets, D12451i) following either tamoxifen or AAV-TBG-Cre injection for 2-3 weeks

3 Therefore, combining GLP-1 medication with a dedicated strength training program creates a synergistic effect, offering a more potent strategy for achieving comprehensive cardiometabolic health improvements and better long-term outcomes compared to relying on the medication alone

They work by helping the body release insulin and reduce glucagon production after meals