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2024 Jan-Feb;32(1):8390

The point is that MOTS-c's safety profile is harder to predict from first principles, and the data needed to narrow that uncertainty do not yet exist

The authors conclude: In this real-world study where half of patients discontinued GLP-1-based treatment within a year after initiation, not losing weight was associated with worse clinical outcomes while larger reductions were associated with decreased risks

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If this occurs, it is important to consult with a healthcare provider