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Berberine has known potential for uterotonic effects and can cross the placenta, with evidence of fetal harm in some animal studies

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Individuals with liver or kidney disease need to approach Tirzepatide with caution, as these conditions could affect medication metabolism and excretion

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Further rounds of 2D and 3D classification yielded a final particle stack of 277.5k particles for final 3D refinement and further rounds of masked refinements to reveal details of more flexible regions of the protein

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