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Dubrow says, pointing to an independent laboratory analysis of products sold as retatrutide

First, the study size and length were not sufficient to assess long-term efficacy and safety

Notably, the KDIGO classification stands as the most frequently employed tool in clinical practice

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In addition, the magnitude of the 1-year mortality reduction observed in GLP-1 RA userslarger than in randomized trialssuggests that residual confounding may persist, including confounding by indication/clinical channeling and a healthy-user effect, and that estimates may be comparator-dependent