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For the primary analysis, a Cox proportional hazards model was used to test for non-inferiority of RYBELSUS 14 mg to placebo for time to first MACE using a risk margin of 1.3

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Metabolic Function & Energy Levels: Experimental research links GH pathways to fat metabolism and muscle maintenance

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however, the decrease in total lean mass was not fully accounted for by proportional losses in individual skeletal muscles (14)