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Our results showed that the contribution of the TSS pathway on de novo cysteine synthesis and GSH generation is only detectable under cystine-restricted conditions, and such function is dimmed when cystine is supplemented at supraphysiological concentrations

Results and discussion Effect of ZIL on cells and tissues We found that ZIL shows less toxicity to human cells (normal fibroblasts, hNF-1) than DMSO at high (10%) concentrations (Fig

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in type 2 diabetes, amylin secretion is typically impaired alongside insulin resistance

The rationale focuses on local gut effects rather than systemic distribution

If a second course is necessary, it cannot start until at least two months after the first