Haematological improvement typically occurs within days to weeks, with reticulocyte counts rising as the marrow responds
It forms when skin cells, keratin, or sebum become trapped beneath the surface
Most users experience mild or no side effects, though injection-site reactions, nausea, dizziness, and headache occur in a subset of patientstypically at rates below 10% in observational data
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Data that remained non-normally distributed and/or heteroscedastic after log transformation were analyzed (not log-transformed, but still 1e13-transformed) with a KruskalWallis test, while normally distributed and homoscedastic data were analyzed with a one-way ANOVA, performed on the log-transformed data as necessary
A single B12 shot continues to deliver benefits for roughly two to four weeks, with peak effects in the first week and a gradual taper after