Infants have the most common symptoms of B 12 deficiency like feeding difficulties, seizures, growth retardation, megaloblastic anemia, developmental delay, hypotonia, microcephaly, lethargy, involuntary movements, irritability, and cerebral atrophy
The pivotal STEP trials for semaglutide and SURMOUNT trials for tirzepatide included thousands of participants with monitoring for suicidal ideation using standardized tools such as the Columbia-Suicide Severity Rating Scale (C-SSRS), and did not demonstrate elevated rates compared to placebo groups
Neurology 68, 13051307
Gathering your supplies You need these items to get started: Your semaglutide medication (pen or vial) A new, unused needle (never reuse needles) Alcohol swabs or soap and water Cotton ball or tissue (optional) FDA-approved sharps container for disposal Check if your medication hasn't expired and looks clear and colorless through the pen window
What We Still Dont Know Despite the growing excitement, experts are urging caution
The evidence base for their use in weight management is very limited, and the MHRA has previously issued safety warnings about unlicensed injectable preparations of this type