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SHOW NOTES [ 00:00 ] GLP-1s, estrogen, and the anti-inflammatory lifestyle [ 00:53 ] Key question for women over: Why is it so hard to lose this weight? [ 03:05 ] Why so many women in perimenopause and menopause feel like their bodies have changed overnight [ 05:00 ] Estrogen, metabolism, gut health, inflammation, and abdominal fat [ 07:00 ] Why estrogen alone does not simply make midlife weight gain disappear [ 08:22 ] The hormone orchestra: estrogen, cortisol, testosterone, progesterone, thyroid, and gut health [ 10:00 ] Why midlife weight gain is due to biology, not personal failure [ 10:30 ] Thyroid health, Hashimotos, and why normal labs may not tell the whole story [ 12:17 ] T4 to T3 conversion, gut health, vitamin D, and thyroid optimization [ 16:37 ] Why deeper thyroid testing matters, especially for women [ 17:21 ] Hashimotos, gluten, gut health, and autoimmune thyroid issues [ 18:35 ] Why being stuck with weight loss can involve more than food or GLP-1s [ 19:29 ] How hormone therapy and GLP-1 medications may work together [ 21:56 ] Declining estrogen and insulin resistance [ 24:40 ] How GLP-1s and estrogen may support metabolic health through different but complementary pathways [ 25:27 ] Why women do not take estrogen simply to lose weight [ 26:00 ] Hot flashes, bone health, and the clinical indications for hormone therapy [ 27:21 ] Estrogen, skin, brain health, heart health, and the importance of understanding the evidence [ 30:29 ] Transdermal estrogen, oral estrogen, and why delivery method matters [ 32:35 ] Vaginal estrogen, vaginal tissue health, urinary tract health, and sexual wellness [ 35:21 ] Topical estrogen cream for the face and skin aging [ 36:36 ] How Dr

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It is unknown if MOTS-c could amplify these or introduce new ones

It is not known if Wegovy will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people