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The long-term data on standard-dose GLP-1 medications continues to be reassuring most cardiovascular and renal outcome trials now extend out 3 to 5 years

You should contact your GP if you experience any of the following : Heavy menstrual bleeding (HMB) : soaking through a pad or tampon every hour for several consecutive hours, passing clots larger than a 50p coin, or bleeding lasting longer than seven days Postcoital or intermenstrual bleeding : any bleeding between periods or after sexual intercourse requires investigation to exclude structural or pathological causes Complete absence of periods (amenorrhoea) for three months or more : particularly if you previously had regular cycles and pregnancy has been excluded Severe pelvic pain : especially if accompanied by fever, unusual discharge, or pain during intercourse, which could indicate infection or other gynaecological conditions Sudden onset of very irregular cycles : if your previously predictable periods become highly erratic without explanation Your GP will likely perform a thorough assessment , including a detailed menstrual history, medication review, and examination if appropriate

Those trials show it can reduce blood sugar and may reduce body weight in people with type 2 diabetes

Patients already onboarded on innovators will not shift as they belong to the affording class, said Pharmarack vice president Sheetal Sapale

Past saturation, extra agonist molecules produce diminishing returns while the dose-dependent side effects keep climbing

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