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Liver (hepatic) and kidney safety considerations are equally important, since some supplements that undergo hepatic metabolism or renal excretion can accumulate or interact with chemotherapeutic drugs leading to hepatotoxicity (e.g., kava, high-dose green tea extract) or nephrotoxicity in patients who already suffer from impaired organ function or taking chemotherapy agents known to be nephrotoxic such as cisplatin (208, 209)

Patients can elect to use topical anesthetic cream if they desire

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Importantly, GLP-1 receptor agonism has been demonstrated in several fibrotic models to lead to inhibition of TGF- signalling

GLP-1 medications reduce appetite, which makes it easy to undereat protein, one of the most essential nutrients for the hair growth cycle