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Related complications such as kidney disease, retinopathy, cardiovascular events, neurological disorders, bone loss, and bone fragility would severely reduce the patients quality of life (Schwartz et al., 2011)

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Thirdly , unregulated prices in pharmacies remain high, which restricts access for households with financial means, and explains the gap between population potential and actual adoption

In this perspective, it is important to understand how CRISPR-Cas9 system can help in the crop improvement by harnessing the precision of genome editing of GSTs in different plant species