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Physiological and pharmacological perspectives of melatonin
(Cyperaceae) extract (500 mg/kg) had a hepatoprotective effect confirmed by decreased the levels of ALT, AST, and alkaline phosphatase (ALP) in APAP overdose patients/mice (Gilani and Janbaz, 1995b)
Placebo: -2.1%
Maternal exposure to polyethylene micro- and nanoplastics impairs umbilical blood flow but not fetal growth in pregnant mice
The largest changes reported in studies occurred over several months while participants continued treatment and dose escalation
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