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Clinical evidence The effectiveness of combination therapy with PIO (1530 mg daily) and tofogliflozin (TOFO 20 mg daily) for 24 weeks was investigated in 32 patients who experienced T2D and NAFLD in an open-label RCT [116]

The evolution of the endocrinology drug pipeline focuses on improving peptide therapeutic delivery and developing effective patient adherence improvement strategies

Sanchez-Gomez A, Alcarraz-Vizan G, Fernandez M, Fernandez-Santiago R, Ezquerra M, Camara A, et al

et al., 2021a

While much has been written about these peptides in their individual capacities, it remains to be seen what results can be achieved with them in combination

That distinction influences why it may not appear in early protocols