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Peer review Peer review information Nature Communications thanks Peng Huang, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
However, RCTs aren't designed to definitively rule out very rare outcomes like MTC or decades-long latency
[1] [2] Be alert to symptoms such as right upper quadrant pain, fever, or jaundice
Site rotation across these regions on a weekly basis is standard practice for all once-weekly subcutaneous peptide administrations, and is particularly important during extended retatrutide dosing studies where repeated injection at a single site can cause localized lipodystrophy or reduced absorption efficiency