Intrigued by the advantages of PROTACs in degrading dysfunctional proteins, herein, we devised an in-situ formed TYR degrader by utilizing the potent catalytic performance of TYR (Fig
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Synthetic peptides can be altered to persist longer in blood or to target specific tissues by attaching small chemical moieties or cyclizing the chain to prevent degradation
The amounts of L-carnitine, acetyl-L-carnitine, L-ARG and NAC that we used (only 500 mg, 250 mg, 500 mg and 50 mg, respectively) were lower than those previously reported to be effective in PCOS patients (12, 30-32)
102772023RT137), Registration date is October 16th, 2023This study has been registered as a clinical trial in China with registration number (ChiCTR2500095544, Passed on January 8th, 2025For subjects under the age of 16, this study obtained the consent of their parents or legal guardians before conducting the test
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