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The fusion peptide demonstrated sleep-promoting effects, influenced neurotransmitter levels (5-HT, glutamate, dopamine, melatonin), and confirmed that the Tat cell-penetrating sequence was the more effective BBB carrier of two tested candidates establishing DSIP as a validated active scaffold for BBB-crossing fusion peptide sleep research and supporting the development of next-generation DSIP-based neuromodulatory tools
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Adjusting GLP-1 drug usage around surgical procedures can impact blood glucose control and complicate treatment for patients with diabetes
In vitro experiments revealed that MC5-R in cardiomyocytes mediates the anti-hypertrophic signaling of -MSH
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