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Each patient starts with a subcutaneous injection of a lower dose once a week for four weeks in the abdomen, upper arm, or thigh

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GLP-1-RAs and metabolic adaptation Metabolic adaptation is the difference between the observed resting energy expenditure and the estimated resting energy expenditure post-weight loss [51]

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Fat is the most energy-dense macronutrient, yielding approximately 9 calories per gram versus 4 calories per gram for carbohydrates and protein

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