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Different stress conditions, including energy depletion, oxidative stress, and hyperosmolarity which emerge in many diseases and some genetic disorders, lead to shortening the erythrocyte lifespan thus facilitating the removal of the damaged and defective erythrocytes [134]
154 RheeS
doi: 10.1073/pnas.1405023111 69 BolvarBEBrown-SuedelANRohrmanBACharendoffCIYazdaniVBelcherJDet al
Children with ASD often exhibit increased oxidative stress and impaired methylation capacity, which are critical in maintaining neurodevelopmental health
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Other toxins like heavy metals, such as mercury from dental fillings, can impair conversion of T4 to T3. 22 High exposure to these toxins, coupled with impaired detoxification due to poor diet, nutrient depletion from chronic stress, and genetic factors, may give them the opportunity to disrupt thyroid function
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